NOAEL – No Observed Adverse Effect Level

01/19/26

“How can we measure the highest dose of a substance that does not cause any statistically significant effect?”

People worry about whether a substance they’re exposed to leads to health complications. One way to understand this is to measure the highest dosage of the substance that organisms can handle before a statistically significant effect occurs. Labeled NOAEL – No Observed Adverse Effect Level, these measurements are fundamental for quantifying safe exposure levels for substances.

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